Spikes trigger LFP waves: the rebuttal

Nauhaus, Busse, Carandini and Dario Ringach published an influential paper in 2009 with pretty convincing evidence that spikes trigger traveling waves of activity visible in LFPs; that these waves travel laterally; and because the dynamics of these waves change during stimulation compared to spontaneous activity, that stimulation modulates functional connectivity. This could imply that a … More Spikes trigger LFP waves: the rebuttal

Setting up a cluster for the analysis of neural array data

As I’ve mentioned before, we’ve been recording from a Utah array for more than a year now. We use a custom Plexon MAP system that allows for the recording of wideband data at 10 kHz over 96 channels. This custom configuration was requested so that we can get spike-free LFPs by preprocessing wideband data with … More Setting up a cluster for the analysis of neural array data

Denoising and spike detection in a Utah array

Our V4 Utah array died last week… and then it worked again this week. It’s pretty amazing that it’s still up and running after about 18 months. It’s gettting noisier, however, and increasingly what’s being recorded is mostly multi-unit activity (MUA). To have any chance of detecting single units, it’s therefore quite important to denoise … More Denoising and spike detection in a Utah array